EVALUATION OF LEAF BASE EXTRACT OF SORGHUM BICOLOR (FAMILY: GRAMINEAE; POACEAE) FOR HAEMATOLOGICAL, IMMUNOMODULATORY AND OTHER PHARMACOLOGICAL ACTIVITIES

ABSTRACT

Sorghum bicolor is an annual plant having its different parts widely used ethnomedicinally for different ailments, which includes blood stimulation and body defence. A number of clinical conditions like cancer, surgery, certain drugs, HIV/AIDS and various stressors affect different components of the immune system thereby allowing opportunistic pathogens to overwhelm the host leading to secondary infections and mortality in such individuals. This therefore shows a great need for investigation of plants with body defence potentials to increase the catalogue of agents that can modify the immune system for subsequent drug development and clinical uses. Also, many scientific reports have shown some drugs to be efficacious, cheap and available, yet toxic. This therefore shows the importance of evaluation of safety profile of a drug intended for short and long term uses.